What is the maximum flow rate for infusing a peripheral solution in mOsm/L?

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The maximum flow rate for infusing a peripheral solution in mOsm/L is 800 mOsm/L. This limit is crucial for ensuring safe and effective administration of fluids. Peripheral veins are more sensitive to osmolarity compared to central veins, as they can experience irritation and damage with higher osmotic solutions.

An infusion above this threshold may lead to complications such as phlebitis or extravasation because the peripheral vasculature is not designed to handle highly osmolar solutions. The goal is to maintain an osmolarity that minimizes discomfort and reduces the risk of complications while providing adequate hydration or nutrient supplementation.

This standard is based on clinical practice guidelines which emphasize the importance of osmotic balance in peripheral infusions. Therefore, solutions with an osmolarity higher than 800 mOsm/L should typically be administered through a central line to avoid these risks.

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